ALSUMA

Pay No More Than $4* Receive ALSUMA Auto-Injectors for as little as $4, often less expensive than generics.* Activate or print your card *See Terms and Conditions

IMPORTANT SAFETY INFORMATION

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ALSUMA may increase your chance of having a heart attack or stroke that can lead to death. This chance is higher in people who have heart disease. Very rarely, certain people, even some without heart disease, have had serious heart-related problems.

ALSUMA is not for people with risk factors for heart disease unless a heart examination is performed and shows no problems. The risk factors for heart disease include but are not limited to:

• High blood pressure
• High cholesterol levels
• Smoking
• Obesity
• Diabetes
• Having a family history of heart disease
• Being a female who has gone through menopause
• Being a male older than 40 years

Do not take ALSUMA if you have:

• Taken any triptans or ergotamine medicines within the last 24 hours, such as almotriptan (AXERT), eletriptan (RELPAX), frovatriptan (FROVA), naratriptan (AMERGE), rizatriptan (MAXALT), sumatriptan (IMITREX), sumatriptan and naproxen (TREXIMET), ergotamines (ERGOMAR, CAFERGOT, or MIGERGOT), and dihydroergotamine (D.H.E. 45, MIGRANAL)
• Narrowing of blood vessels to the legs, arms, stomach, or kidneys (e.g., peripheral vascular disease)
• Heart disease or a history of heart disease
• Uncontrolled high blood pressure
• Migraines that cause temporary paralysis on one side of your body
• Basilar migraine (rare form of migraine with symptoms including but not limited to: dizziness, double vision, loss of balance, confusion, slurred speech, hearing change)
• Had a stroke, transient ischemic attacks, or problems with your blood circulation
• Are allergic to sumatriptan or any of the other ingredients in ALSUMA

Serotonin syndrome is a serious and life-threatening problem that can be caused by ALSUMA, especially if used with antidepressant medicines called selective serotonin reuptake inhibitors (SSRIs) or serotonin norepinephrine reuptake inhibitors (SNRIs). Make sure to tell your healthcare professional if you take SSRIs, SNRIs, or monoamine oxidase inhibitors (MAOIs).

Call your healthcare professional if you have symptoms of serotonin syndrome, which include but are not limited to:

• Mental changes (e.g., seeing things that are not there, unusual tension, and restlessness)
• Fast heartbeat
• Changes in blood pressure
• High body temperature
• Tight muscles
• Trouble walking
• Nausea, vomiting, or diarrhea

Tell your healthcare professional about all of the medicines (both prescription and nonprescription), vitamins, and herbal supplements that you take.

Before taking ALSUMA, tell your healthcare professional about all of your medical conditions, including if you:

• Have high cholesterol
• Have diabetes
• Smoke
• Have gone through menopause
• Have heart disease or a family history of heart disease or stroke
• Have had epilepsy or seizures
• Are pregnant or plan to become pregnant. It is not known if ALSUMA will harm your unborn baby.
• Are breastfeeding or plan to breastfeed. ALSUMA passes into your breast milk and may harm your baby.

Use of ALSUMA

• Take ALSUMA exactly as your healthcare professional tells you
• Take ALSUMA as soon as your symptoms of a migraine or cluster headache start, although it may be given at any time during an attack
• The usual dose is a single injection given just below the skin in the side of your thigh or upper arm. Do not inject ALSUMA into a vein or muscle.
• You may take a second injection from a second auto-injector, at least one hour after the first dose, if your migraine or cluster headache symptoms come back. Do not take more than 2 doses in a 24-hour period.
• If your symptoms do not get better after the first injection, do not give a second injection for the same attack without first talking with your healthcare provider

ALSUMA can cause serious side effects or even death. Serious side effects can include:

• Heart attacks
• Fast heartbeat
• Increase in blood pressure
• Stroke
• Changes in mental status (e.g., agitation, hallucinations, or coma)
• Changes in color or sensation in your fingers and toes (e.g., Raynaud syndrome)
• Poor blood flow to the arms or legs
• Poor blood flow to the gastrointestinal tract

Get medical help right away if you have:

• Severe tightness, pain, pressure, or heaviness in your chest, throat, neck, or jaw
• Shortness of breath or wheezing
• Sudden or severe stomach pain
• Hives
• Swelling of your tongue, mouth, or throat
• Problems seeing
• Unusual weakness or numbness
• Nausea or vomiting
• Bloody diarrhea
• High temperature
• Unusual sweating

The most common side effects of ALSUMA include but are not limited to:

• Bleeding, swelling, redness, bruising, and pain at the injection site
• Tingling or numbness in your fingers or toes
• Dizziness
• Warm, hot, or burning feeling to your face (flushing)
• Feeling of heaviness or pressure
• Discomfort or tightness in the chest, neck, throat, nose, or jaw
• Feeling weak, drowsy, or tired
• Feeling strange
• Muscle pain

Keep ALSUMA and all medicines out of the reach of children.

All brands are trademarks of their owners.

INDICATIONS

ALSUMA (sumatriptan injection) 6 mg/0.5 mL Auto-Injector for subcutaneous use is a prescription medicine that contains sumatriptan and is used to treat adults who have been diagnosed with migraine or cluster headaches.

ALSUMA is not used to treat other types of headaches or used to prevent or lessen the number of migraine or cluster headaches (a cluster headache is one-sided head pain that may involve tearing of the eyes and a stuffy nose).

It is not known if ALSUMA is safe or effective in people younger than 18 or ≥65 years of age.

Please see Full Prescribing Information, Patient Information, and Patient Instructions for Use.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-332-1088.

Terms and Conditions

By using the ALSUMA $4 Co-pay Card, you acknowledge that you currently meet the eligibility criteria and will comply with the terms and conditions described below:

• The Card is not valid for prescriptions that are eligible to be reimbursed, in whole or in part, by Medicaid, Medicare, or other federal or state healthcare programs (including any state prescription drug assistance programs and the Government Health Insurance Plan available in Puerto Rico [formerly known as "La Reforma De Salud"])
• The Card is not valid for prescriptions that are eligible to be reimbursed by private insurance plans or other health or pharmacy benefit programs that reimburse you for the entire cost of your prescription drugs
• Patients must be 18 or older
• By using the Card, patients will pay only $4 per prescription. Savings are limited to $150 per month for 12 uses. The Card may be used once per month and is good for a maximum savings of $1,800 per calendar year
• You must deduct the value received under this program from any reimbursement request submitted to your insurance plan, either directly by you or on your behalf
• The Card cannot be combined with any other rebate or coupon, free trial, or similar offer for the specified prescription
• The Card will be accepted only at participating pharmacies
• The Card is not health insurance
• This offer is good only in the United States and Puerto Rico
• The Card is limited to one per person during this offering period and is not transferable
• Pfizer reserves the right to rescind, revoke, or amend the Card without notice

Offer valid from 8/24/11 to 12/31/13.

No membership fees apply.

For help with the ALSUMA $4 Co-pay Card, call 1-800-732-7530, or write:
Pfizer, ATTN: ALSUMA
P.O. Box 2229
Morrisville, PA 19067-9853
www.pfizer.com

The health information contained herein is provided for educational purposes only and is not intended to replace discussions with a healthcare provider. All decisions regarding patient care must be made with a healthcare provider, considering the unique characteristics of the patient.

This product information is intended only for residents of the United States. The products discussed herein may have different product labeling in different countries. All brands are trademarks of their owners.

ALSUMA is a registered trademark of Pfizer Inc. Other brands listed are trademarks of their respective owners.